T41S (p.Thr41Ser) variant of NTRK3 (NT-3 growth factor receptor)
T41S (p.Thr41Ser) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
T41S (p.Thr41Ser) variant details
- p.Thr41Ser
- ExAC rs750256958
- gnomAD rs750256958
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- REVEL 0.62
- CADD 21.30
- PolyPhen-2 0.97
- SIFT 0.74
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available