T41A (p.Thr41Ala) variant of NTRK3 (NT-3 growth factor receptor)
T41A (p.Thr41Ala) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
T41A (p.Thr41Ala) variant details
- p.Thr41Ala
- gnomAD rs1224048634
- Missense
- Variant Prioritization Score for Impact Estimate 0.631
- REVEL 0.67
- CADD 21.70
- PolyPhen-2 0.97
- SIFT 0.74
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available