S39I (p.Ser39Ile) variant of NTRK3 (NT-3 growth factor receptor)
S39I (p.Ser39Ile) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
S39I (p.Ser39Ile) variant details
- p.Ser39Ile
- TOPMed rs1339674722
- Missense
- Variant Prioritization Score for Impact Estimate 0.705
- REVEL 0.69
- CADD 25.80
- PolyPhen-2 0.85
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available