R89H (p.Arg89His) variant of NTRK3 (NT-3 growth factor receptor)
R89H (p.Arg89His) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R89H (p.Arg89His) variant details
- p.Arg89His
- cosmic curated COSV58112
- ESP rs374069724
- ExAC rs374069724
- TOPMed rs374069724
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.39
- CADD 21.80
- PolyPhen-2 0.20
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available