R47W (p.Arg47Trp) variant of NTRK3 (NT-3 growth factor receptor)
R47W (p.Arg47Trp) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
R47W (p.Arg47Trp) variant details
- p.Arg47Trp
- cosmic curated COSV58107
- ExAC rs771206956
- TOPMed rs771206956
- gnomAD rs771206956
- Missense
- Variant Prioritization Score for Impact Estimate 0.636
- REVEL 0.56
- CADD 29.90
- PolyPhen-2 0.24
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available