N35D (p.Asn35Asp) variant of NTRK3 (NT-3 growth factor receptor)
N35D (p.Asn35Asp) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
N35D (p.Asn35Asp) variant details
- p.Asn35Asp
- TOPMed rs1381478314
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.37
- CADD 22.80
- PolyPhen-2 0.03
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available