L5V (p.Leu5Val) variant of NTRK3 (NT-3 growth factor receptor)
L5V (p.Leu5Val) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
L5V (p.Leu5Val) variant details
- p.Leu5Val
- cosmic curated COSV58118
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.10
- CADD 23.30
- PolyPhen-2 0.06
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available