L5F (p.Leu5Phe) variant of NTRK3 (NT-3 growth factor receptor)
L5F (p.Leu5Phe) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
L5F (p.Leu5Phe) variant details
- p.Leu5Phe
- gnomAD rs1332907152
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.11
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available