L57P (p.Leu57Pro) variant of NTRK3 (NT-3 growth factor receptor)
L57P (p.Leu57Pro) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
L57P (p.Leu57Pro) variant details
- p.Leu57Pro
- ExAC rs779387312
- gnomAD rs779387312
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.60
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available