L53F (p.Leu53Phe) variant of NTRK3 (NT-3 growth factor receptor)
L53F (p.Leu53Phe) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L53F (p.Leu53Phe) variant details
- p.Leu53Phe
- cosmic curated COSV58120
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.30
- CADD 20.40
- PolyPhen-2 0.00
- SIFT 0.70
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available