I85V (p.Ile85Val) variant of NTRK3 (NT-3 growth factor receptor)
I85V (p.Ile85Val) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
I85V (p.Ile85Val) variant details
- p.Ile85Val
- TOPMed rs1401376854
- gnomAD rs1401376854
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.45
- CADD 23.20
- PolyPhen-2 0.07
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available