I85M (p.Ile85Met) variant of NTRK3 (NT-3 growth factor receptor)
I85M (p.Ile85Met) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
I85M (p.Ile85Met) variant details
- p.Ile85Met
- gnomAD rs1458667131
- Missense
- Variant Prioritization Score for Impact Estimate 0.53
- REVEL 0.67
- CADD 23.30
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available