I85L (p.Ile85Leu) variant of NTRK3 (NT-3 growth factor receptor)
I85L (p.Ile85Leu) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
I85L (p.Ile85Leu) variant details
- p.Ile85Leu
- TOPMed rs1401376854
- gnomAD rs1401376854
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.48
- CADD 23.60
- PolyPhen-2 0.11
- SIFT 0.01
- Most common in the East Asian population (allele frequency 0.00033)
- Structural context available