I76T (p.Ile76Thr) variant of NTRK3 (NT-3 growth factor receptor)
I76T (p.Ile76Thr) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
I76T (p.Ile76Thr) variant details
- p.Ile76Thr
- Ensembl rs2054014854
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.22
- CADD 22.90
- PolyPhen-2 0.28
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available