H92Y (p.His92Tyr) variant of NTRK3 (NT-3 growth factor receptor)
H92Y (p.His92Tyr) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
H92Y (p.His92Tyr) variant details
- p.His92Tyr
- Ensembl rs2046770421
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.35
- CADD 22.70
- PolyPhen-2 0.04
- SIFT 0.05
- Most common in the East Asian population (allele frequency 0.0006)
- Structural context available