G19E (p.Gly19Glu) variant of NTRK3 (NT-3 growth factor receptor)
G19E (p.Gly19Glu) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
G19E (p.Gly19Glu) variant details
- p.Gly19Glu
- cosmic curated COSV58139
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.28
- CADD 22.10
- PolyPhen-2 0.06
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available