D50G (p.Asp50Gly) variant of NTRK3 (NT-3 growth factor receptor)
D50G (p.Asp50Gly) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
D50G (p.Asp50Gly) variant details
- p.Asp50Gly
- ExAC rs748721173
- gnomAD rs748721173
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.45
- CADD 22.30
- PolyPhen-2 0.06
- SIFT 0.73
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available