A96T (p.Ala96Thr) variant of NTRK3 (NT-3 growth factor receptor)
A96T (p.Ala96Thr) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
A96T (p.Ala96Thr) variant details
- p.Ala96Thr
- cosmic curated COSV10044
- ExAC rs765088970
- TOPMed rs765088970
- gnomAD rs765088970
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.40
- CADD 20.60
- PolyPhen-2 0.16
- SIFT 0.39
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available