A8P (p.Ala8Pro) variant of NTRK3 (NT-3 growth factor receptor)
A8P (p.Ala8Pro) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A8P (p.Ala8Pro) variant details
- p.Ala8Pro
- ExAC rs766330065
- gnomAD rs766330065
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.17
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available