A34T (p.Ala34Thr) variant of NTRK3 (NT-3 growth factor receptor)
A34T (p.Ala34Thr) in NTRK3 (NT-3 growth factor receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
A34T (p.Ala34Thr) variant details
- p.Ala34Thr
- ExAC rs766063980
- TOPMed rs766063980
- gnomAD rs766063980
- Missense
- Variant Prioritization Score for Impact Estimate 0.488
- REVEL 0.35
- CADD 21.30
- PolyPhen-2 0.28
- SIFT 0.70
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available