W4C (p.Trp4Cys) variant of NTRK2 (Q16620)
W4C (p.Trp4Cys) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
W4C (p.Trp4Cys) variant details
- p.Trp4Cys
- gnomAD 9-84670760-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.54
- REVEL 0.49
- CADD 32.00
- PolyPhen-2 0.91
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available