S49F (p.Ser49Phe) variant of NTRK2 (Q16620)
S49F (p.Ser49Phe) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
S49F (p.Ser49Phe) variant details
- p.Ser49Phe
- gnomAD rs1371476425
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.39
- CADD 20.60
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available