S41F (p.Ser41Phe) variant of NTRK2 (Q16620)
S41F (p.Ser41Phe) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
S41F (p.Ser41Phe) variant details
- p.Ser41Phe
- ExAC rs760689213
- TOPMed rs760689213
- gnomAD rs760689213
- Missense
- Variant Prioritization Score for Impact Estimate 0.54
- REVEL 0.47
- CADD 22.40
- PolyPhen-2 0.14
- SIFT 0.05
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available