S3P (p.Ser3Pro) variant of NTRK2 (Q16620)
S3P (p.Ser3Pro) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and published literature.
S3P (p.Ser3Pro) variant details
- p.Ser3Pro
- gnomAD 9-84670755-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.12
- CADD 21.60
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Literature evidence available