R42W (p.Arg42Trp) variant of NTRK2 (Q16620)
R42W (p.Arg42Trp) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
R42W (p.Arg42Trp) variant details
- p.Arg42Trp
- TOPMed rs1420992400
- gnomAD rs1420992400
- Missense
- Variant Prioritization Score for Impact Estimate 0.768
- REVEL 0.78
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available