R42Q (p.Arg42Gln) variant of NTRK2 (Q16620)
R42Q (p.Arg42Gln) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
R42Q (p.Arg42Gln) variant details
- p.Arg42Gln
- cosmic curated COSV99451
- Ensembl rs76060730
- Missense
- Variant Prioritization Score for Impact Estimate 0.698
- REVEL 0.71
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available