R42G (p.Arg42Gly) variant of NTRK2 (Q16620)
R42G (p.Arg42Gly) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
R42G (p.Arg42Gly) variant details
- p.Arg42Gly
- gnomAD 9-84670872-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.743
- REVEL 0.75
- CADD 22.70
- PolyPhen-2 1.00
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available