P65S (p.Pro65Ser) variant of NTRK2 (Q16620)
P65S (p.Pro65Ser) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
P65S (p.Pro65Ser) variant details
- p.Pro65Ser
- gnomAD 9-84670941-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.05
- CADD 10.90
- PolyPhen-2 0.11
- SIFT 0.84
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available