P65L (p.Pro65Leu) variant of NTRK2 (Q16620)
P65L (p.Pro65Leu) in NTRK2 (Q16620) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
P65L (p.Pro65Leu) variant details
- p.Pro65Leu
- rs1470117060
- gnomAD 9-84670941-C-CT
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.507
- CADD 26.20
- Most common in the Amish population (allele frequency 0.0011)
- Structural context available
- Literature evidence available