P60H (p.Pro60His) variant of NTRK2 (Q16620)
P60H (p.Pro60His) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
P60H (p.Pro60His) variant details
- p.Pro60His
- cosmic curated COSV99454
- ExAC rs769089926
- gnomAD rs769089926
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- REVEL 0.42
- AlphaMissense 0.10
- MetaLR 0.95
- MetaSVM 0.86
- CADD 20.60
- PolyPhen-2 0.90
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available