M12V (p.Met12Val) variant of NTRK2 (Q16620)
M12V (p.Met12Val) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
M12V (p.Met12Val) variant details
- p.Met12Val
- gnomAD 9-84670782-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.14
- CADD 20.60
- PolyPhen-2 0.05
- SIFT 0.27
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available