L58F (p.Leu58Phe) variant of NTRK2 (Q16620)
L58F (p.Leu58Phe) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
L58F (p.Leu58Phe) variant details
- p.Leu58Phe
- gnomAD 9-84670922-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.664
- REVEL 0.70
- CADD 26.80
- PolyPhen-2 0.97
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available