I5V (p.Ile5Val) variant of NTRK2 (Q16620)
I5V (p.Ile5Val) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
I5V (p.Ile5Val) variant details
- p.Ile5Val
- TOPMed rs981883098
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.06
- CADD 22.20
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available