F25L (p.Phe25Leu) variant of NTRK2 (Q16620)
F25L (p.Phe25Leu) in NTRK2 (Q16620) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F25L (p.Phe25Leu) variant details
- p.Phe25Leu
- Ensembl rs2131266562
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.04
- CADD 16.90
- PolyPhen-2 0.00
- SIFT 0.66
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available