W25L (p.Trp25Leu) variant of NTRK1 (P04629)
W25L (p.Trp25Leu) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
W25L (p.Trp25Leu) variant details
- p.Trp25Leu
- gnomAD 1-156861008-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.20
- MetaLR 0.06
- MetaSVM -0.98
- CADD 22.20
- PolyPhen-2 0.04
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available