W25C (p.Trp25Cys) variant of NTRK1 (P04629)
W25C (p.Trp25Cys) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
W25C (p.Trp25Cys) variant details
- p.Trp25Cys
- gnomAD 1-156861009-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.38
- MetaLR 0.18
- MetaSVM -0.92
- CADD 23.90
- PolyPhen-2 0.33
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available