W15C (p.Trp15Cys) variant of NTRK1 (P04629)
W15C (p.Trp15Cys) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
W15C (p.Trp15Cys) variant details
- p.Trp15Cys
- gnomAD 1-156860979-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.19
- MetaLR 0.14
- MetaSVM -0.93
- CADD 18.70
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available
- Literature evidence available