W12L (p.Trp12Leu) variant of NTRK1 (P04629)
W12L (p.Trp12Leu) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
W12L (p.Trp12Leu) variant details
- p.Trp12Leu
- gnomAD 1-156860969-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.20
- MetaLR 0.15
- MetaSVM -0.90
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available