S21T (p.Ser21Thr) variant of NTRK1 (P04629)
S21T (p.Ser21Thr) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
S21T (p.Ser21Thr) variant details
- p.Ser21Thr
- gnomAD rs1415403729
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -1.02
- CADD 16.00
- PolyPhen-2 0.00
- SIFT 0.57
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available