S14R (p.Ser14Arg) variant of NTRK1 (P04629)
S14R (p.Ser14Arg) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S14R (p.Ser14Arg) variant details
- p.Ser14Arg
- gnomAD rs1441623333
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.16
- MetaLR 0.12
- MetaSVM -1.03
- CADD 15.60
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available