R3R (p.Arg3Arg) variant of NTRK1 (P04629)
R3R (p.Arg3Arg) in NTRK1 (P04629) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data, published literature, and structural context.
R3R (p.Arg3Arg) variant details
- p.Arg3Arg
- rs755716153
- gnomAD 1-156842153-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.853
- REVEL 0.91
- MetaLR 0.77
- MetaSVM 0.65
- CADD 28.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available