P19S (p.Pro19Ser) variant of NTRK1 (P04629)
P19S (p.Pro19Ser) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P19S (p.Pro19Ser) variant details
- p.Pro19Ser
- Ensembl rs2102879055
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.11
- MetaLR 0.12
- MetaSVM -1.05
- CADD 14.90
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available