P19Q (p.Pro19Gln) variant of NTRK1 (P04629)
P19Q (p.Pro19Gln) in NTRK1 (P04629) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P19Q (p.Pro19Gln) variant details
- p.Pro19Gln
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.11
- MetaLR 0.07
- MetaSVM -1.05
- CADD 12.30
- PolyPhen-2 0.00
- SIFT 0.08
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available