L2P (p.Leu2Pro) variant of NTRK1 (P04629)
L2P (p.Leu2Pro) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L2P (p.Leu2Pro) variant details
- p.Leu2Pro
- gnomAD 1-156860939-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.39
- MetaLR 0.28
- MetaSVM -0.65
- CADD 22.60
- PolyPhen-2 0.45
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available