L28P (p.Leu28Pro) variant of NTRK1 (P04629)
L28P (p.Leu28Pro) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
L28P (p.Leu28Pro) variant details
- p.Leu28Pro
- gnomAD 1-156861017-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- REVEL 0.54
- MetaLR 0.54
- MetaSVM 0.15
- CADD 27.30
- PolyPhen-2 0.97
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available