L26P (p.Leu26Pro) variant of NTRK1 (P04629)
L26P (p.Leu26Pro) in NTRK1 (P04629) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
L26P (p.Leu26Pro) variant details
- p.Leu26Pro
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.679
- REVEL 0.73
- MetaLR 0.61
- MetaSVM 0.35
- CADD 28.20
- PolyPhen-2 0.99
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available