L26M (p.Leu26Met) variant of NTRK1 (P04629)
L26M (p.Leu26Met) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L26M (p.Leu26Met) variant details
- p.Leu26Met
- gnomAD 1-156861010-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.48
- MetaLR 0.53
- MetaSVM 0.03
- CADD 23.20
- PolyPhen-2 0.99
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available