L23P (p.Leu23Pro) variant of NTRK1 (P04629)
L23P (p.Leu23Pro) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
L23P (p.Leu23Pro) variant details
- p.Leu23Pro
- gnomAD 1-156861002-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.504
- REVEL 0.49
- MetaLR 0.32
- MetaSVM -0.42
- CADD 24.80
- PolyPhen-2 0.42
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available