L23M (p.Leu23Met) variant of NTRK1 (P04629)
L23M (p.Leu23Met) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L23M (p.Leu23Met) variant details
- p.Leu23Met
- gnomAD 1-156861001-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.10
- MetaLR 0.13
- MetaSVM -0.98
- CADD 20.10
- PolyPhen-2 0.01
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available