L22P (p.Leu22Pro) variant of NTRK1 (P04629)
L22P (p.Leu22Pro) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
L22P (p.Leu22Pro) variant details
- p.Leu22Pro
- gnomAD 1-156860999-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.499
- REVEL 0.45
- MetaLR 0.40
- MetaSVM -0.27
- CADD 27.20
- PolyPhen-2 0.58
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available